Viruses replicate within cells that recognize them by using or diverting resources from the host. In turn, the organism is able to detect that it is infected and responds, but viruses have different mechanisms to counter our defenses, so the responses we build are different depending on the pathogen and may even be harmful to the organism. These science digests will be dedicated to studies that explore questions about where and how the SARS-CoV-2 virus circulates in our bodies, what means it uses to replicate within cells and elude our immune system and about whether the type of immune response that we set up is efficient to eliminate the virus and prevent us from being reinfected. In this topic we will also explore studies related to the effect of the virus on metabolism and how healthy eating can influence the outcome of viral infection.